Aquacalm™ has recently be granted Indexed status by the US FDA. See full press release at:  Aquacalm™ Becomes Second Drug Indexed by the US FDA.  

Aquacalm™ is Indexed for the sedation and anesthesia of ornamental finfish. Aquacalm™ is not for use in fish intended for human or animal consumption. Sedation may be necessary in situations such as strip spawning for hatchery rearing, transporting fish from supplier to wholesaler or retailer, photographing fish as part of a strategic marketing approach, or removal of fish from exhibit tanks prior to cleaning. Anesthesia may be necessary in situations where detailed fish examination or minor surgical procedures are to be conducted.

Aquacalm™ has been tested on representative ornamental finfish species, but has not been tested on all fish species. The effect of Aquacalm™ may vary between (and within) species, depending upon age and physical condition of fish, and under different water conditions. Sedate or anesthetize fish in water with temperature and pH close to the temperature and pH of rearing water.

Each gram of Aquacalm™ powder contains 1 gm of metomidate hydrochloride. Aquacalm™ acts on the central nervous system to induce sedation or anesthesia in fish immersed in water containing the drug.

More on FDA Indexing: - In order to be legally marketed, an animal drug product intended for a minor species must be Approved, Conditionally Approved, or Indexed by the FDA. Aquacalm™® is INDEXED.  For more information from the FDA regarding Indexing, visit the following FDA websites:

Aquacalm Product Label and Directions - FDA Website

List of Indexed Drugs for Ornamental Fish - FDA Website